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Dermacyn® EZyma™ Hydrogel
45 g

The essential components of EZyma™ is a novel combination of Hypochlorous Acid (HOCl) and silicone hydrogel for the easy management of eczema and dermatitis flares.

  • Fast itch relief
  • Non-steroidal
  • Anti-microbial & Anti-inflammatory
  • Safe for all ages


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The active ingredient in EZyma™ hydrogel, hypochlorous acid, is able to inhibit up to 86% of the release of
histamine from mast cells, which is responsible for skin redness, swelling and itchiness (hallmark of allergy)


Reduces itch

Reduces redness

Eliminates infection


82% of users experience rapid itch relief by day 3 of using EZyma™ Hydrogel¹


¹ Draelos, Z. D., MD. (2012). Antipruritic Hydrogel for the Treatment of Atopic Dermatitis: An Open Label Pilot Study. Cutis, 90, 97-102

Fast & Effective

Consistent application helps to maintain optimum environment for healing

Ezyma Wash affected area

Clean the affected area and let dry

Ezyma apply affected area

Shake the bottle well and apply a thin layer of EZyma™ Hydrogel*

*If prescribed or necessary, apply topical steroid first

Ezyma apply moisturiser

Apply a thin layer of moisturiser of choice


I’ve been looking for quick remedies to my son’s eczema condition. Since using EZyma™, my son’s skin has been more hydrated and less angry (red and inflamed) looking. I would certainly recommend this product to all the busy moms out there. The spray-on application is hassle-free as well!

MichelleWorking Mum


 Yes, EZyma™ is safe for all ages and is widely used in hospitals and clinics.

Yes. EZyma™ can be used with other emollients or topical steroids.

For effective results, shake the bottle well before use.

Warning: For external use only.

Yes. EZyma™ can be used more than three times a day depending on the severity of the eczema case.

Eczema​ flare ups may happen any time due to various reasons including infections, allergens and even stress.

It is advisable to continue using EZyma™ as a maintenance therapy. Eczema is a lifelong disease that cannot be cured but may be appropriately managed. The recurrence of eczema cannot be avoided but the severity of subsequent flare ups can be reduced by managing it properly.

Till date, there is no reported adverse effect of using EZyma™. However, EZyma™ should be avoided by those with known hypersensitivity to silicone.

Clinical Study

Antipruritic Hydrogel for the Treatment of Atopic Dermatitis: An Open-Label Pilot Study

Zoe Draelos, MD

A 14-day pilot study on 17 adults with mild to moderate atopic dermatitis with associated pruritus demonstrated that treatment with EZyma™ hydrogel could relieve skin itchiness in 82% of study subjects by day 3 post-treatment. Futhermore, 76% of study subjects also experienced a significant improvement in disease condition based on investigator global assessment.

A New Steroid-Free Regimen for the Treatment of Atopic Dermatitis

R. Smith, MD

A second open label pilot study on 15 subjects (aged 7 months to 49 years old) with mild to moderate atopic dermatitis showed that treatment with EZyma™ hydrogel in combination with an emollient could reduce skin itchiness, dryness, redness, burning and pain by 50% or more. Besides, symptoms such as induration, excoriation, erythema, and lichenification reduced by 60% or more. Based on subject satisfaction survey, EZyma™ hydrogel was rated “very good”.

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